Matty Ryze on Crypto’s Third Product-Market Fit: How AI Is Redefining the Next Wave After Stablecoins and Gambling | Bitcoin.com News Podcast

About this episode

“After stablecoins and gambling proved crypto’s first two PMFs, AI is lined up as the third.”

In this episode of the Bitcoin.com News Podcast, Matty Ryze (@mattyryze) joins David Sencil (@_dsencil) to explore why AI is emerging as crypto’s next major product-market fit — and how this convergence could reshape everything from DeFi to data markets.

Ryze breaks down the three historical phases of crypto adoption — stablecoins, on-chain gaming/gambling, and now AI-integrated infrastructure — showing how each wave drives utility, liquidity, and mainstream engagement. The discussion spans AI agents, decentralized compute, model marketplaces, and what builders can learn from crypto’s past PMF cycles to build the next breakout protocols.

• Why AI is crypto’s third product-market fit
• Lessons from stablecoins and gambling as early crypto successes
• The rise of on-chain AI agents and compute networks
• How data, incentives, and infrastructure are merging
• What this new AI x crypto era means for developers and investors

A must-listen for founders, investors, and technologists who want to understand how AI and blockchain are colliding to create crypto’s most scalable, real-world use case yet.

🎙️ Host: David Sencil – Bitcoin.com News Podcast
💼 Guest: Matty Ryze – Web3 Founder & Investor
🔗 Learn more: bitcoin.com | @mattyryze | @_dsencil

💡 In this episode:🎧

Hosted by Bitcoin.com News Media

Sep 12, 2025

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